Lactase: the enzyme that determines how you feel after drinking milk

Молоко, сир і йогурт: молочні продукти, для перетравлення яких потрібен фермент лактаза
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Молоко, сир і йогурт: молочні продукти, для перетравлення яких потрібен фермент лактаза

Lactose intolerance is one of the most common causes of discomfort after consuming milk in adults. It is related to the function of the enzyme lactase, which is responsible for breaking down lactose in the intestine. If there is not enough lactase, symptoms such as bloating, gas, or diarrhea may occur. This is not a disease in the classical sense, but a normal variation for many people. Let’s look at how lactase works, why its levels decrease with age, and what to do about it without extremes.

There are two types of people:
those who can drink milk without problems, and those who later regret that decision.

And the difference comes down to one enzyme.

Molecular structures and chemical formulas illustrating the action of the lactase enzyme

What lactase is and how it works

Lactase is an enzyme produced in the small intestine.

Its task is simple:
to break down lactose (milk sugar) into:

  • glucose
  • galactose

In this form, they can already be absorbed.

If there is enough lactase — there are no problems. If not — a completely different story begins.

Symptoms of lactose intolerance

Symptoms of lactose intolerance occur because lactose is not fully broken down in the small intestine and enters the large intestine, where it is fermented by bacteria. The severity of symptoms may vary depending on individual tolerance and the amount of lactose consumed.

Most often, symptoms appear 30–120 minutes after consuming milk or dairy products:

  • bloating
  • excess gas
  • gurgling in the abdomen
  • discomfort or cramps
  • diarrhea
  • a feeling of heaviness after meals

In most cases, these symptoms do not pose a health risk, but they can affect well-being and quality of life. It is important to note that similar symptoms may also occur in other gastrointestinal conditions.

If symptoms recur regularly after consuming dairy products, it is advisable to consult a doctor to clarify the cause and receive personalized recommendations.

If you recognize these symptoms — next, let’s understand why this happens.

Symptoms of lactose intolerance: intestinal discomfort

Why lactase decreases

And here is an interesting point.

In most people worldwide, lactase activity decreases with age. This is called “adult-type lactase deficiency.”

That is:
this is not a malfunction of the body
this is an evolutionary norm

And the ability to drink milk in adulthood is rather an exception related to genetics.

Table 1. Types of lactase activity

Type What happens Who it is typical for
High activity Lactose is well absorbed Some Europeans
Reduced activity Partial digestion Most adults
No activity Lactose is not broken down Rare cases

What happens in lactase deficiency

Undigested lactose enters the large intestine.

And there, bacteria “happily” begin to ferment it.

Result:

  • bloating
  • gas formation
  • discomfort
  • sometimes diarrhea

And this is important: this is not an allergy.

discomfort with lactase deficiency

Lactose intolerance vs milk allergy

These are often confused.

Lactose intolerance:

  • an enzyme issue
  • unpleasant but not dangerous

Milk protein allergy:

  • an immune reaction
  • can be serious

These are different mechanisms and require different approaches.

How to tell if lactase is the problem

A typical scenario:

  • you drank milk
  • after 30–120 minutes, discomfort appeared

But it’s better not to rely on symptoms alone for diagnosis.

There are methods:

  • hydrogen breath test
  • elimination diet

Milk, yogurt, hard cheese: lactose intolerance

How to live with it normally

And here’s the good news: this is not a big deal.

What helps:

  • reduce the amount of milk
  • choose fermented products (yogurt, cheese)
  • use lactose-free options
  • if needed — lactase enzyme

And there is no need to completely “eliminate” dairy if you tolerate small amounts.

Table 2. What is usually better tolerated

Product Why
Yogurt Partially broken-down lactose
Hard cheese Minimal lactose
Lactose-free milk Lactose already broken down
Kefir Bacteria help digestion

Questions and answers

Can lactase be “restored”?

No. But the diet can be adapted.

Do you need to completely avoid milk?

Not always. It depends on tolerance.

Why was it fine before, but not now?

Because lactase activity decreases with age.

Is lactose intolerance dangerous?

No. It’s a matter of comfort, not a threat.

Conclusions

Lactase is a small enzyme with a big impact.

In short:
the problem is not the milk, but how the body processes it.

And this doesn’t need to be “treated” — it needs to be understood and adapted to.

References

  1. National Institutes of Health. Lactose intolerance.
  2. National Health Service. Lactose intolerance.
  3. European Food Safety Authority. Lactose digestion and tolerance.
  4. Misselwitz B, et al. Lactose malabsorption and intolerance. Gut. 2019.
  5. Swallow DM. Genetics of lactase persistence. Annual Review of Genetics. 2003.
  6. Deng Y, Misselwitz B, et al. Lactose intolerance in adults. BMJ. 2015.

About the Author

Author Photo

Nikolay Bondarenko is a Ukrainian dermatologist and expert in skin diseases.   A graduate of Ukraine's leading medical university, he specializes in diagnosing and treating dermatological issues.   As the author of numerous expert articles, he actively contributes to the development of dermatology and shares his knowledge with the medical community.





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