L-Theanine and Magnesium: A Calm Formula Without Drowsiness

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Дівчина тримає чашку з чаєм, який містить амінокислоту L-теанін

In a world of constant noise, messages, and news, calmness has become the new luxury.
Modern people are looking for a way to relax — without sedative effects, without dependence, without losing focus.

Two ingredients that have gained popularity among professionals and consumers — L-theanine (an amino acid from green tea) and magnesium (the anti-stress mineral).
Together, they create a unique formula that reduces anxiety, improves focus, and helps the brain maintain balance.

Nutraceuticals for calmness without drowsiness in tablet and capsule form

How L-theanine works

L-theanine is a natural amino acid that affects alpha brain waves, which are responsible for a state of relaxed alertness.
Unlike sedatives, it does not cause drowsiness and provides a sense of calm and mental clarity.

Main effects:

  • reduces cortisol levels during stress;

  • increases attention and focus;

  • improves sleep quality without a sedative effect;

  • boosts dopamine and serotonin levels.

Man sitting at a laptop

The role of magnesium in the calmness formula

Magnesium is involved in over 300 enzymatic reactions, including the regulation of the nervous system.
Its deficiency is one of the most common causes of irritability, insomnia, and muscle tension.

Highly bioavailable forms of magnesium, such as citrate, glycinate, L-threonate, are especially effective for stress and fatigue.
They act gently, supporting the balance of neural signals and restoring GABA receptor sensitivity.

Table 1. Comparison of L-theanine and magnesium effects

Parameter L-theanine Magnesium
Source Green tea leaves Minerals (citrate, glycinate, L-threonate)
Main action Relaxation without drowsiness, focus Anti-stress, stabilizes nervous system
Time of effect 30–60 min after intake Cumulative effect 1–2 weeks
Additional effect Improves sleep and focus Reduces muscle tension, headache
Bioavailability High Varies depending on form
Best combination With magnesium, GABA, or melatonin With L-theanine or vitamin B6

Calm+Focus drink for support of focus and concentration, headphones on desk

Synergy: L-theanine + Magnesium

At the Vitafoods Europe 2025 exhibition, this combination was presented as “smart calm” — a next-generation formula for intelligent relaxation.

Together they:

  1. Support the balance of neurotransmitters — GABA, serotonin, and dopamine.

  2. Reduce the body’s stress response without suppressing brain activity.

  3. Improve sleep quality without causing morning fatigue.

  4. Reduce muscle tension and tension headaches.

 

Table 2. Delivery systems of L-theanine and magnesium in nutraceuticals (2025)

Form Example composition Benefits Target audience
Gummies (chewable tablets) L-theanine 200 mg + Mg citrate 100 mg Convenient form, pleasant taste Youth, office workers
Sleep spray L-theanine + magnesium + melatonin Fast effect, easy falling asleep People with insomnia
Shot or “Calm+Focus” drink L-theanine + Mg + B6 + L-tryptophan Supports focus and concentration Students, IT specialists
“Stress Balance” capsules Mg glycinate + L-theanine Comprehensive action People with chronic stress
Liposomal form Mg L-threonate + L-theanine High bioavailability, innovative form Older users

Girl stretching before sleep

Practical recommendations

  • L-theanine can be taken during the day for focus or in the evening for relaxation.

  • Magnesium is best taken after dinner or before sleep.

  • Optimal doses: L-theanine 200–400 mg/day, magnesium 200–400 mg/day.

  • Avoid forms with magnesium oxide — it is poorly absorbed.

  • Combination with vitamin B6 enhances magnesium’s effect.

FAQ

Does L-theanine cause drowsiness?
No. It relaxes without suppressing brain activity; on the contrary, it improves focus.

Can it be taken with coffee or energy drinks?
Yes, L-theanine even mitigates caffeine side effects.

Which form of magnesium is best for the nervous system?
Magnesium glycinate and L-threonate are the most effective for the brain.

Can it be taken during pregnancy?
L-theanine — with caution, only after consultation. Magnesium is allowed in most forms.

When is the effect noticeable?
L-theanine — within 30–60 min, magnesium — after 7–10 days of regular use.

Conclusions

The L-theanine + magnesium formula is a natural alternative to synthetic tranquilizers.
It works gently, does not suppress, does not cause dependence, but restores inner balance, mental clarity, and stable mood.

In 2025, this combination became one of the most popular in nutraceuticals for mental health — from “anti-stress” gummies to liposomal formulas.

References

  1. Nobre A. C. et al. L-theanine, a natural anxiolytic: mechanism and evidence. Nutr Neurosci, 2023.

  2. Boyle N. et al. Magnesium supplementation and mood regulation. J Clin Nutr, 2024.

  3. Vitafoods Europe 2025 Report. Smart calm formulations: magnesium and theanine synergy.

  4. Benton D. L-theanine and caffeine: interaction in mental performance. Biol Psychol, 2022.

  5. Lindberg J. S. Bioavailability of magnesium forms in nutraceuticals. Nutrients, 2024.

About the Author

Author Photo

Nikolay Bondarenko is a Ukrainian dermatologist and expert in skin diseases.   A graduate of Ukraine's leading medical university, he specializes in diagnosing and treating dermatological issues.   As the author of numerous expert articles, he actively contributes to the development of dermatology and shares his knowledge with the medical community.





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