The modern pace of life and constant stress pose new challenges to the immune system.
The search for natural and safe ways to support immunity has led to growing interest in beta-glucans — natural polysaccharides found in mushrooms, oats, barley, and yeast.
At the Vitafoods Europe 2025 exhibition, beta-glucans were one of the key topics: they are presented not only as classic immunomodulators, but also as a next-generation ingredient in chewable forms, functional waters, and combined complexes.
What are beta-glucans?
Beta-glucans are soluble dietary fibers that interact with immune system cells (macrophages, dendritic cells) via Dectin-1 and CR3 receptors.
-
They activate innate immunity, enhancing the body’s response to infections.
-
At the same time, they have a balancing effect, reducing excessive inflammation.
Immunity in a new format: applications in 2025
Vitafoods showcased several new approaches:
-
Chewable gummies with beta-glucans for children and adults — a convenient form for daily use.
-
Functional drinks enriched with fibers — combining hydration with immune support.
-
Combined complexes with vitamin C, zinc, and probiotics — synergy for the immune barrier function.
Such delivery systems make nutrients more accessible and attractive to consumers.
Research and clinical data
-
A meta-analysis by Vetvicka & Richter, 2020 showed that beta-glucans reduce the incidence of upper respiratory tract infections by 20–25%.
-
In the study by Jesenak et al., 2013, children taking yeast-derived beta-glucans experienced one-third fewer cold episodes.
-
Oats and barley are sources of β-1,3/1,4-glucans, which are also associated with lower cholesterol levels.
Table 1. Sources of beta-glucans
| Source | Type of beta-glucan | Main effect |
|---|---|---|
| Yeast | β-1,3/1,6 | Immunomodulation |
| Mushrooms (shiitake, reishi) | β-1,3/1,6 | Adaptogenic and anti-inflammatory effect |
| Oats, barley | β-1,3/1,4 | Cholesterol reduction, cardiovascular support |
Applications in modern forms
Today, beta-glucans go beyond classic capsules and powders.
Thanks to new delivery systems, they have become more convenient for daily use and accessible to different consumer groups.
The market offers chewable gummies for children and adults, functional drinks for active people, and combined complexes for those frequently affected by colds.
Each form has its advantages, increasing compliance and nutrient utilization efficiency.
Table 2. Applications in modern forms (2025)
| Form | Target audience | Features |
|---|---|---|
| Chewable gummies | Children, adults | High compliance |
| Functional drinks | Athletes, office workers | Combination of hydration and immunity |
| Combined complexes | People with frequent colds | Synergy with vitamin C, zinc, probiotics |
Conclusion
Beta-glucans remain one of the most promising nutrients for supporting the immune system.
New delivery systems make them accessible and attractive, aligning with modern nutraceutical trends.
For doctors, they are an important tool in infection prevention; for consumers, a simple and safe solution for daily health support.
References
-
Vetvicka V., Richter J. Beta-glucan: Supplement or drug? Front Immunol. 2020.
-
Jesenak M. et al. Immunomodulatory effect of pleuran (β-glucan from Pleurotus ostreatus) in children with recurrent respiratory infections. Int Immunopharmacol. 2013.
-
Kogan G, Kocher A. Role of yeast cell wall polysaccharides in pig nutrition and health protection. Livestock Science. 2007.
-
Chen J, Seviour R. Medicinal importance of fungal beta-(1→3), (1→6)-glucans. Mycol Res. 2007.
-
EFSA. Health claims related to beta-glucans from oats and barley and blood cholesterol. EFSA Journal. 2011.
About the Author
